Lapidus Lab

Group Members

Lisa Lapidus

Professor, Physics and Astronomy

Adjunct Professor, Biochemistry and Molecular Biology

Michigan State University

Biomedical Physical Sciences Bldg.

567 Wilson Rd, Rm. 4227

East Lansing, MI 48824

(517) 884-5656

(517) 353-4500 (fax)



  • B.S., University of Michigan, 1991
  • A.M., Harvard University, 1993
  • Ph.D., Harvard University, 1998

Past Research Interests

  • Synchronization and Stochastic Behavior of Electrons in a Penning Trap

 Jim Carrey and Conan O'Brien find this topic cool.

  • Single Molecule Fluorescence
  • RNA folding



Kinshuk Srivastava

Postdoctoral Fellow

Research Experience

  • Ph.D., IIT Bombay, peptide models to investigate protein folding principles
  • Postdoc, University of North Carolina, Prof. Barry R. Lentz lab, investigation of structural regulation of FXa by phosphatidyl serine
  • currently investigating how prion aggregation is kinetically controlled by early stage reconfiguration dynamics of monomer using optical spectroscopic Trp-Cys quenching method.

Suresh Nagarajan

Postdoctoral Fellow

Research Experience

Suresh is interested in studying the early events of aggregation in amyloid self-assembly. Specifically his study focus on how the monomer dynamics of amyloid beta peptide controls the rate of assembly into toxic oligomer and large aggregates.

  • 2014-2015: Visiting Scientist, Hebrew University of Jerusalem, Israel
  • 2012-2014: Research Fellow, CSIRO-Deakin University, Australia
  • 2009-2012: Research Associate, Emory University, United States
  • 2007-2009: Postdoc, Bar-Ilan University, Israel ?PhD: University of Madras, 2008

Trieu Nguyen

Postdoctoral Fellow

Research Experience

  • Physical chemistry (MSc, Sungkyunkwan University, South Korea).
  • Micro-, nanofludics and Lab-on-a-chip. (PhD 2015, University of Twente, Netherlands. Group: BIOS-Lab on a Chip, Project: microfluidics for energy conversion.)
  • Microfluidic mixers for investigating protein folding.

Bimlesh Ojha

Postdoctoral Fellow

Research Experience

  • 2007-2011: PhD in Biophysical Chemistry from Indian Institute of Technology Guwahati (IITG), Guwahati, Assam, India, Investigated the effect of synthetic amphiphiles on the photophysics of proteins
  • 2011-2012: Postdoctoral Fellow with Dr. Deguo Du at Florida Atlantic University, Florida, USA, Investigated the effect of polyelectrolytes on the aggregation propensity of Abeta40 peptide
  • 2013-2015: JSPS Postdoctoral Fellow with Prof. Yasushi Kawata at Tottori University, Tottori, Japan, Investigated the assembly of alpha-synuclein onto a folded target protein viz. GroEL-apical domain
  • 2016-Till date Postdoctoral Fellow with Prof. Lisa Lapidus at Michigan State University, MI, USA, Investigating the effect of various inhibitor molecules on the monomer dynamics of alpha-synuclein

Dena Izadi

Graduate Student, Physics and Quantitative Biology

Research Experience

  • Fast folding events in proteins using laser spectroscopy
  • Fused Silica Ultra-fast Mixer Fabrication using two different techniques- UCLA nanolab, Lurie Nanofabrication Facility at University of Michigan, and W.M. Keck Microfabrication Facility at MSU
  • Protein folding studies using single molecule force spectroscopy techniques- Collaboration work with Matthew Comstock lab at Michigan State University

Terry Ball


Research experience

  • Protein Purification
  • Chromatography
  • Molecular Biology