SCIENCE AT THE EDGE SEMINAR SERIES Quantitative Biology & Modeling Seminar Friday, 24 February 2012 at 11:30am Room 1400 Biomedical and Physical Sciences Bldg. Refreshments at 11:15 Speaker: Michael Kosorok Department of Biostatistics and National Institute of Statistical Sciences, University of North Carolina at Chapel Hill Title: Personalized Medicine and Artificial Intelligence Abstract: Personalized medicine is an important and active area of clinical research involving high dimensional data. In this talk, we describe some recent design and methodological developments in clinical trials for discovery and evaluation of personalized medicine. Statistical learning tools from artificial intelligence, including machine learning, reinforcement learning and several newer learning methods, are beginning to play increasingly important roles in these areas. We present illustrative examples in treatment of depression and cancer. The new approaches have significant potential to improve health and well being.