SCIENCE AT THE EDGE SEMINAR SERIES

Quantum Biology / Gene Expression in Development and Disease Seminar

Friday, 30 November 2012 at 11:30am

Room 1400 Biomedical and Physical Sciences Bldg.

Refreshments at 11:15

Speaker: Gerry Wright
         Department of Biochemistry and Biomedical Sciences
         McMaster University
         
Title:   Resisting Resistance: Overcoming Antibiotic Resistance with 
         Small Molecules

Abstract:
Resistance to antibiotics is among the greatest challenges to modern health
care. Resistance to all classes of antibiotics has emerged while new antibiotic
drug discovery has lagged, resulting in a growing crisis.  To address this
challenge, new approaches to antibiotic drug discovery and new therapeutic
strategies need to be considered.  One such approach is the combination of
bioactive compounds with antibiotics to overcome resistance, such antibiotic
adjuvants have the capacity to extend the life and spectrum of known drugs.
Our efforts to block resistance directly and indirectly using small molecule
antibiotic adjuvants will be presented.