Special Joint Department of Mathematics /
Quantitative Biology / Gene Expression in Development & Disease Seminar

Note special day and time!

Tuesday, 26 February 2013 at 11:00 am

Room 1400 Biomedical and Physical Sciences Bldg.

Refreshments at 10:45 am

Speaker:  Yaoqi Zhou, School of Informatics, Indiana University-Purdue University at Indianapolis

Title:  Shedding light on the dark matter in the universe of protein structures and protein-RNA interactions

Most biological activities are directed and regulated by proteins. Despite significant efforts, the structures and functions for the majority of proteins remain unknown. On one hand, increasing structure coverage of protein sequences since 2007 has not led to any expansion of the structure space itself. On the other hand, function annotations continue to utilize antiquated homology-searching tools that have limited sensitivity. In this talk, I will discuss two new bioinformatic tools that take you deeper into the protein structure space and protein-RNA interaction space that none has ever been there before.