SCIENCE AT THE EDGE SEMINAR SERIES

Quantitative Biology / Gene Expression in Development & Disease Seminar

Friday, 29 March 2013 at 11:30am

Room 1400 Biomedical and Physical Sciences Bldg.

Refreshments at 11:30

Speaker:  Matthew Rockman, Department of Biology and Center for Genomics & Systems Biology, New York University

Title:  Genetic Consequences of Mating-system Evolution in C. Elegans

Abstract:
C. elegans, the workhorse model organism for studies of development and behavior, reproduces primarily by self-fertilization in hermaphrodites. Its recent ancestors, however, were obligate outcrossers, with separate sexes. The transition from outcrossing to selfing altered the selective regime in which these animals live, and it simultaneously transformed the genetic structure of the species. I'll show how mating-system evolution in C. elegans has affected the distribution of genetic and phenotypic variation in this species, focusing on two genetic case studies: early embryogenesis and mating behavior.