Friday, 06 September 2013 at 11:30 am
Room 1400 Biomedical and Physical Sciences Bldg.
Refreshments at 11:15 am.
Speaker: Ilya Nemenman, Department of Physics, Department of Biology, and Computational & Life Sciences Initiative, Emory University
Title: Information Processing in Cellular Signaling
Abstract:
Signal or information processing and shaping of a response (a.k.a, signal transduction,
regulation, sensing) is a common function performed by organisms on all levels of
organization. In this talk, we will study information processing in cellular systems
to answer questions like: Does the fidelity of information processing matter
evolutionarily? What are the fundamental physical limits to the fidelity of information
processing set by the intrinsic fluctuations in the cellular biochemical machinery?
How close the cells come to these limits? What can they do to improve the performance?
After introducing the general theoretical framework, we will address these and related
questions in the specific experimental context of mammalian NF-kB signaling.